Applications: This equipment is a one-step solid dispersion granulator developed by our company. It is designed to transform drug crystal forms, enhance the solubility of poorly soluble drugs, and improve bioavailability.
Principle: The liquid mixture is transported by a peristaltic pump to a two-fluid pneumatic spray gun, where it is atomized into droplets by compressed air. These droplets come into full contact with air heated by an electric heater, drying and solidifying instantaneously. A portion of the dried particles settles into the collection bucket at the bottom of the drying chamber with the airflow. The exhaust gas passes through a dust removal device for secondary gas-solid separation to collect the final product.
Features:
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Feeding System: Uses a peristaltic pump for liquid delivery, ensuring a constant and continuous feeding rate.
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Multi-form Spraying System: Optional spraying methods including atomizing spray guns or centrifugal atomizing disks, selectable based on customer requirements.
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Customized Services: Options such as inlet air dehumidification systems, nitrogen protection circulation systems, and organic solvent recovery systems can be provided based on specific needs.
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Compliance: Fully compliant with GMP standards with three-level password authorization. Process parameters are automatically controlled by PLC, with all data stored online and exportable via USB.
Specifications and main technical parameters:
| Model | SD150 | SD220 | SD700 | SD1000 |
|---|---|---|---|---|
| Capacity (L/h) | 0.1~1 | 0.5~2 | 30~40 | 60~80 |
| Min. Test Sample (L) | 0.05 | 0.1 | 3 | 10 |
| Air Temperature (℃) | Room Temp ~300 | |||
| Fan Power (kW) | 0.75 | 1.5 | 7.5 | 11 |
| Electric Heating Power (kW) | 3 | 6 | 27 | 30 |
| Power Supply | 380V/50Hz Three-phase 5-wire | |||
| Air Source Pressure (Mpa) | 0.6 | 0.6 | >0.6 | >0.6 |
| Overall Dimensions (mm) | 850×900×850 | 850×900×1120 | 2400×1480×2250 | 3200×1620×2650 |
| Machine Weight (kg) | 190 | 250 | 2000 | 3000 |
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